Education for lifelong brain health
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PACIFIc neuroscience insitute foundation
Precision Brain Health Program
A personalized, proactive approach to memory, cognition, and lifelong brain health.
Your brain health is shaped by many factors over a lifetime. Our Precision Brain Health Program brings together neuroscience, precision medicine, prevention, lifestyle, education, and emerging research to help you better understand your brain health and what you can do to support it.
Whether you are focused on healthy brain aging, concerned about family history or future risk, noticing changes in memory or thinking, or already navigating cognitive impairment, we help make the science of brain health understandable, useful, and actionable.
The opportunity
There Is More We Can Do About Brain Health Than Many People Realize
The processes that affect memory and cognition can develop over many years. At the same time, a growing body of research has identified 14+ potentially modifiable factors that may influence cognitive health and dementia risk across the lifespan.
These include cardiovascular and metabolic health, physical activity, sleep, hearing, mood, social connection, nutrition, cognitive engagement, and other individual factors.
The opportunity is to think about brain health earlier, more comprehensively, and more personally. We don't have to wait until significant cognitive problems have developed.
A more complete view
Your Brain Is Unique. Your Approach to Brain Health Should Be, Too.
Personalized
There is no single pathway to healthy brain aging. Likewise, cognitive decline does not arise for the same reasons in all people. Genetics, medical history, biomarkers, lifestyle, environment, and other factors can differ substantially from one person to another.
Proactive
Brain health deserves attention throughout life. Identifying modifiable risks and opportunities earlier may provide more time to protect health, strengthen resilience, and support cognition.
Multidimensional
Sleep, exercise, nutrition, metabolic and vascular health, mood, sensory health, medications, social connection, cognitive engagement, and other factors interact. Precision Brain Health considers the bigger picture rather than viewing each factor in isolation.
Science-Informed
We draw from established neuroscience and prevention research while following advances in precision medicine, biomarkers, lifestyle medicine, nutrition, supplements, and multimodal approaches to cognitive health.
Our goal is to help distinguish what is well established, what is promising, and what may reasonably be worth considering for an individual.
Who it is for
Who Is Precision Brain Health For?
You don't need to have memory problems to start thinking about your brain health.
I want to protect my brain health.
Explore ways to support cognition, resilience, and healthy brain aging.
I have a family history or known risk.
Better understand what risk may mean and which factors may be modifiable.
I've noticed changes in memory or thinking.
Learn about cognitive changes, possible contributors, and when clinical evaluation may be appropriate.
I'm already navigating cognitive impairment.
Access education, research updates, resources, and support for individuals and families facing cognitive concerns.
Programs
Explore Precision Brain Health
Choose the level of education and engagement that works for you.
Year-long education
Annual Precision Brain Health Education Program
A year-long educational program for individuals seeking a deeper, structured approach to understanding and supporting their brain health.
Focused guidance
1-Hour Precision Brain Health Education Consultation
A focused individual educational consultation with David A. Merrill, MD, PhD, for people who want expert guidance in understanding brain-health information, questions, and potential next steps.
Medical services
Looking for Clinical Care?
If you are seeking medical evaluation, diagnosis, treatment, medication management, or other clinical care for memory, cognition, or brain health, visit the Pacific Brain Health Center at Pacific Neuroscience Institute to explore available clinical services and providers.
Events & Media
Learn With Us
Talks, events, and community conversations on brain-health.
Connect with educational events on neuroscience, memory, healthy aging, lifestyle medicine, cognitive wellness, and related fields.
Discover upcoming programs from our Institute and collaborators working to advance brain health.
Explore a growing collection of selected videos, presentations, interviews, podcasts, stories, and other educational media.
BLOG POSTs
Brain Health Insights
Useful science. Thoughtful interpretation. Practical implications.
Explore articles about memory and cognition, healthy brain aging, dementia prevention, exercise, sleep, metabolic health, nutrition, supplements, biomarkers, and emerging research.
We also examine individual supplements and interventions: what the evidence suggests, why formulation and dose can matter, who might reasonably consider them, and when they may not be worthwhile.
Memory & Cognition
Are These Small Changes in Memory a Big Warning?
A closer look at subtle memory changes, possible warning signs, and when a clinical evaluation may be appropriate.
Science & Research
The Science Behind Precision Brain Health
Brain health is increasingly moving toward earlier identification of risk, attention to multiple modifiable factors, and more individualized approaches.
Research has identified numerous potentially modifiable factors associated with dementia risk. Multidomain clinical trials have tested the effects of addressing several areas (including exercise, nutrition, cognitive activity, and vascular health) together.
Precision-medicine research asks a further question: can we do better by understanding the particular combination of risks, strengths, biological findings, and potentially modifiable contributors relevant to each individual?
Precision Brain Health follows this evolving science and helps translate it into practical education.
Resources
Supplement Education & Dispensary
Better information for better supplement decisions.
Supplements bearing the same ingredient name can differ in formulation, potency, purity, and manufacturing quality. And more ingredients on a label do not necessarily make a better product.
Our educational content examines whether particular supplements are worth considering, what the research actually studied, and when formulation or dose may matter.
For those who choose to use supplements, Dr. Merrill's Fullscript dispensary provides access to products from vetted manufacturers in one convenient resource. A site-wide discount is available to everyone, with additional discounts available in some circumstances.
Purchasing through the dispensary is optional. The goal is to help people make better-informed supplement decisions, not simply to sell supplements.
Program leadership
David A. Merrill, MD, PhD
Director, Precision Brain Health Program
David A. Merrill, MD, PhD, is a physician-scientist whose work focuses on brain health, healthy cognitive aging, prevention, and personalized approaches to cognitive decline.
His clinical and research work has explored how multiple potentially modifiable factors can influence cognitive health and how advances in neuroscience, precision medicine, and lifestyle intervention can be translated into practical strategies.
As Director, Dr. Merrill guides the scientific direction of the Precision Brain Health Program and the development of its educational programs, resources, and initiatives.
Stay connected
Keep learning about your brain health.
Get new articles, upcoming talks and events, research updates, and news about Precision Brain Health programs delivered to you.
Science-forward education for memory, cognition, and lifelong brain health.
Education, Not Medical Care
Precision Brain Health provides educational information and services. For medical evaluation, diagnosis, or treatment, visit the Pacific Brain Health Center.
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